This is not a complete list of side effects and others may occur. Portions of this document last updated: April 01, 2020. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. This is not a complete list of side effects and others may occur. You may report side effects to FDA at 1-800-FDA-1088. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. We comply with the HONcode standard for trustworthy health information -, Drug class: miscellaneous antihyperlipidemic agents. Stop taking bempedoic acid and seek medical attention right away if you have signs of tendon rupture: sudden pain, swelling, bruising, or tenderness; or a snapping or popping sound in any of your joints (rest the joint until you receive medical care or instructions). Show all parts of this monograph; Drug action; Indications and dose; Interactions; Side-effects; Pregnancy; Breast feeding; Medicinal forms; Drug … If you require BNF for Children, use BNFC. Drug information provided by: IBM Micromedex. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. 8 However, bempedoic acid was associated with hyperuricemia … This content does not have an Arabic version. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. [Ref], Very common (10% or more): Hyperuricemia (26%), Common (1% to 10%): Clinically significant hyperuricemia, gout, Uncommon (0.1% to 1%): Increase in creatine kinase. All rights reserved. Platelet count elevations appeared to be asymptomatic as they did not result in an increased risk of thromboembolic events or require medical intervention. Ankle, knee, or great toe joint pain arm, back, or leg pain bloody … If you experience any of these symptoms, stop taking bempedoic acid and call your doctor immediately or get emergency medical treatment: severe pain, redness, warmth, tenderness, or … Our Nexlizet (bempedoic acid and ezetimibe) Tablets, for Oral Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Advertising revenue supports our not-for-profit mission. Uses for Bempedoic Acid Bempedoic acid has the following uses: Bempedoic acid is an adenosine triphosphate-citrate lyase (ACL) inhibitor indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of … © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Common (1% to 10%): Benign prostatic hyperplasia. Gout occurred in 1.5% of patients receiving this drug compared to 0% of placebo-treated patients. Bempedoic acid, an adenosine triphosphate-citrate lyase (ACL) inhibitor, is an antilipemic agent. All rights reserved. Bempedoic acid side effects. Tell your doctor if any of these symptoms are severe or do not go away: muscle spasms; back pain; pain in hands or feet; Some side effects can be serious. Nexletol (bempedoic acid)." Bempedoic acid may cause side effects. 1. Safety and Side Effects of Bempedoic Acid As anticipated, in light of its lack of active metabolites in skeletal muscles, bempedoic acid added to maximally tolerated statin therapy was not associated with an increased incidence of muscular disorders or serious adverse events compared to placebo in the CLEAR Harmony trial. Stop taking bempedoic acid and seek medical attention right away if you have signs of tendon rupture: sudden pain, swelling, bruising, or tenderness; stiffness, movement problems; or; or a … The more commonly reported adverse reactions have included upper respiratory tract infections, muscle spasms, hyperuricemia, back pain, abdominal pain or discomfort, bronchitis, extremity pain, anemia, and elevated liver enzymes. Although not all of these side effects may occur, if they do occur they may need medical attention. Available for Android and iOS devices. 13 The trial confirms the expectation that bempedoic acid does not induce muscle‐related side effects. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Side Effects. This site complies with the HONcode standard for trustworthy health information: verify here. Our Nexletol (bempedoic acid) Tablets, for Oral Use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. What are the possible side effects of bempedoic acid (Nexletol)? Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Along with its needed effects, a medicine may cause some unwanted effects. Check with your doctor immediately if any of the following side effects occur: Some side effects may occur that usually do not need medical attention. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Medically reviewed by Drugs.com. This content does not have an English version. Drug information provided by: IBM Micromedex. Copyright © 2020 IBM Watson Health. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You may report them to the FDA. You may report side effects to the FDA at 1-800-FDA-1088. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for BEMPEDOIC ACID. Along with its needed effects, a medicine may cause some unwanted effects. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. low red blood cells (anemia)--pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter. See our safe care and visitor guidelines, plus trusted coronavirus information. Call your doctor for medical advice about side effects. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. Though bempedoic acid does not lower LDL-C nearly as much as the PCSK9 inhibitors, its appeal may lie in a lower expected price and oral administration. Mayo Clinic does not endorse companies or products. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. This drug compared with 1.1 % of patients receiving this drug compared to 0 % of patients this. Not all of these side effects of statin therapy of bempedoic acid, an adenosine triphosphate-citrate lyase ( ). 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Provided for educational purposes only and may not be sold, redistributed or otherwise used for commercial purposes and products. Your medicine label and package material is provided for educational purposes only and may not be sold, or! The latest medication news, new drug approvals, alerts and updates more than 24,000 prescription drugs, over-the-counter and...