The editor of a medical journal has a challenging role. Article. A meta-analysis5 of 6 RCTs (N = 906) comparing oral azithromycin and oral doxycycline for acne reported severe diarrhea necessitating discontinuation in 4 patients. The Family Physicians Inquiries Network Clinical Inquiries series in Canadian Family Physician is coordinated by Rick Guthmann, MD, MPH, Editor-in-Chief for the series. A retrospective cohort study evaluating use of oral erythromycin in middle-aged adults found that it was associated with a higher risk of sudden cardiac death.7 The authors reviewed 1 249 943 person-years of follow-up of oral erythromycin use in a Tennessee Medicaid population (average age 45 years; 25% of the cohort older than 65 years) and found 1.2 deaths per 1000 person-years (incidence rate ratio of 2.01; 95% CI 1.08 to 3.75). But the editor also has to cope with other concerns, including ethical issues, opposition within the editorial board, and conflict with disgruntled authors. Life Sciences Librarian at the University of Washington in Seattle, Wash. Sign In to Email Alerts with your Email Address. Interested in research on Fellowships and Scholarships? JAMA's Fishbein Fellowship. Editor, informed Institute for Clinical Evaluative Sciences 1997 - 2007 10 years. Formación reglada en editorialismo médico: ¿por qué, quién, cuándo, cómo? and the status of the journal. The write path. Only 9% of editors in the United States send at least half of the papers to reviewers outside their own country, compared with 41% of editors in the United Kingdom and 73% in other countries, and 69% do not feel bound to follow the advice they receive concerning acceptance of papers. of papers. If interested in submitting questions or writing answers for this series, go to or e-mail [email protected] Enter multiple addresses on separate lines or separate them with commas. Thank you for your interest in spreading the word on The College of Family Physicians of Canada. A 2012 systematic review of studies of adverse effects largely associated with minocycline divided the types of adverse effects into 3 categories: early dose-related effects on single organ systems (vestibular, gastrointestinal, dermatologic), hypersensitivity reactions (pneumonitis, eosinophilic nephritis, serum sickness), and autoimmune disorders (SLE, autoimmune hepatitis, polyarteritis nodosa).1 While minocycline commonly produced adverse effects in single organ systems (332 of 1906 patients [17.4%] in 29 RCTs), it did not often result in discontinuation of the drug (79 of 2143 patients [3.7%] in 34 RCTs withdrew as a result of adverse effects), but there were more withdrawals due to adverse effects than with placebo (relative risk of 1.08; 95% CI 1.03 to 1.13). methods: election by a scientific society (49 [30%]), nomination by the previous The potential harms or adverse effects of this antibiotic use are described below. Tetracyclines also cause dizziness, headache, and photosensitivity in 2% of patients (strength of recommendation [SOR] A: based on meta-analyses of randomized controlled trials [RCTs]). © 2008-2020 ResearchGate GmbH. Two systematic reviews of antibiotic treatments for acne,4,5 both predominantly involving teenagers and young adult populations, described gastrointestinal symptoms (nausea, vomiting, and abdominal pain) as the most common adverse effects of erythromycins (incidence of 4% with erythromycin stearate and 20% with erythromycin base2). Only 9% of editors in the United States send edited had 6060 (27300/1000 [maximum/minimum]) citations, 234 (740/31) source All rights reserved. Clinical journals are usually edited by practicing clinicians who are self-taught part-time editors, but willing to accept further training. similar characteristics. Can Fam Physician 2010;56:213 (Eng), 215 (Fr). that editors are selected for their clinical or academic rather than editorial as medical editors (eg, Eric Wooltorton at, Cet article se trouve aussi en français à la. Anonymous mail survey to editors of the 262 peer-reviewed clinical journals that had received at least 1000 citations in the 1994 Science Citation Index. Physicians most commonly select from 3 classes of medications (tetracyclines, macrolides, and clindamycin) when indicating oral antibiotics for the treatment of acne. All content in this area was uploaded by Nicholas Pimlott, Surprisingly, there are still very few opportunities for. One systematic review of 22 mostly open-label studies evaluating the efficacy of azithromycin in acne treatment found few gastrointestinal adverse effects and noted the absence of photosensitivity.6 The authors of the 2 previously mentioned meta-analyses3,4 also described cardiac conduction abnormality as a rare adverse effect, based on case reports (incidence specific to acne patients not supplied). Most cases of PTC induced by minocycline occurred in teenagers and young adults. To test the hypothesis that editors of medical specialist clinical journals were recruited from active clinicians rather than those with evident ability or training as editors. Caroline Richardson, M.D., the Dr. Max and Buena Lichter Research Professor of Family Medicine and Editor-in-Chief of the Annals of Family Medicine, along with nine other journal editors, write, “In the wake of disproportionate deaths of Black people due to racial injustice and the COVID-19 pandemic, a fundamental transformation is warranted, and family physicians can play a key role.”